Frequently asked questions (FAQ)

Before starting treatment

I am unable to get pregnant. What should I do?

If you have been unable to get pregnant for more than 1 year (or for more than 6 months if you are over 35), we recommend contacting your gynaecologist or booking an initial examination and consultation directly at an assisted reproduction centre.

How does the initial consultation work?

You can book a consultation by phone or e-mail. The initial consultation can take place in person or online via Teams. It lasts approximately one hour, and the doctor who leads the consultation will become your attending physician.

What examinations do I need?

We recommend testing the hormones AMH, TSH, fT4 and prolactin. For the male partner, a semen analysis is advisable. All these examinations can be performed directly at our clinic, or you can provide us with current results from another medical facility.

What is AMH and what does it mean if its value is low?

AMH (anti-Müllerian hormone) indicates a woman's ovarian reserve, meaning how many eggs she still has available. A low AMH level does not mean that pregnancy is impossible, but it may indicate that achieving pregnancy naturally could be more difficult and that the response to hormonal stimulation may be weaker. Based on the result, the doctor will recommend the most suitable treatment approach.

What if my partner has a poor semen analysis result?

Reduced sperm quality can often be addressed. Depending on the results, different types of treatment or sperm selection methods may be recommended, such as MSS or MACS, which help select sperm with higher fertilisation potential.

Do we have to undergo IVF immediately?

Not always. It depends on the cause of infertility and the examination results. In some cases, timed intercourse or IUI (less invasive methods) may be sufficient. We recommend IVF if simpler approaches do not bring the expected result.

How often do we need to visit the clinic?

During stimulation, 1–2 ultrasound check-ups are usually needed, followed by a clinic visit on the day of egg retrieval and embryo transfer. In donor programmes, a large part of the preparation can be completed remotely. A personal visit is then required only on the day of the donor's oocyte pick up and the transfer itself.

Can I get pregnant even during menopause?

Yes. If you have frozen embryos, they can be transferred after hormonal preparation even without a natural menstrual cycle. If no embryos are available, treatment with donated eggs (OD programme) may be an option. This makes pregnancy possible even for women whose ovarian function has ceased.

Medication use and application

When do I start stimulation or hormonal preparation?

The start of stimulation always depends on the type of protocol prescribed by your doctor. Stimulation usually starts on the 2nd–3rd day of the menstrual cycle. Your coordinator will tell you the exact date and will also prepare a detailed treatment schedule for you.

What if I cannot tell whether I have started menstruating or am only spotting?

Sometimes it can be difficult to determine the exact start of menstruation, especially if the bleeding is initially weak or appears only as spotting. We usually consider the first day of the cycle to be the moment when the bleeding is clearly red and stronger. However, if medication is applied already during spotting, there is no need to worry – the cycle will not be invalidated.

What if my period started only in the evening?

If you started menstruating after 7 p.m., count the following day as the first day of menstruation.

Can I start preparation if my period has unexpectedly shifted?

Yes. Even if the cycle is irregular, preparation can be started according to the prescribed protocol.

How are injections applied?

Most injections are applied subcutaneously into the abdominal area, into the so-called skin fold. The needles are very thin and the application is usually minimally painful.

Do I have to apply injections or take medication at exactly the same time?

Stimulation injections are applied in the morning, ideally before 9 a.m. Try to keep approximately the same time, but a small time shift is not a problem.

What if I forgot to apply Ovitrelle at the scheduled time?

In this case, contact the clinic hotline immediately (you will find the phone number on your stimulation protocol). Never apply Ovitrelle at a different time without consulting the clinic.

Ovarian puncture

What should I bring on the day of OPU and how should I prepare?

Before ovarian puncture, you must be fasting, meaning no food, drink or smoking from midnight. Bring a nightgown or a long T-shirt, slippers, a light snack and something to drink. After the puncture, you will be monitored by medical staff for at least 2 hours. You can then leave for home with an escort.

What should my partner expect?

Your partner will come with you on the day of the puncture and provide a sperm sample in the collection room. Unless the doctor has instructed otherwise, we recommend approximately 2 days of sexual abstinence.

Can my partner stay with me in the recovery room?

This depends on current capacity. If you are alone in the room, your partner may stay with you the whole time. If the room is shared, your partner's presence is unfortunately not possible. If your partner would like to rest on the adjacent bed, this is possible by agreement and after payment of a fee of CZK 800 / EUR 30.

What can I expect after the puncture?

Ovarian puncture is usually well tolerated. However, you may feel mild cramps or pressure in the lower abdomen, or pain similar to menstrual pain. A mild feeling of bloating is also common.

What restrictions apply after the puncture?

After the puncture, avoid sexual intercourse, sitting baths and visits to swimming pools or outdoor pools. Limit physical activity and do not exercise.

How will I receive information about embryo development?

Your coordinator will inform you about embryo development on days 1, 3 and 5 of culture by e-mail during the morning. If embryo monitoring is used, you will receive information every day. If a fresh transfer is performed on day 5, the information will be provided directly at the clinic.

Embryo Transfer/FET

How should I prepare for transfer?

On the day of transfer, your bladder should be slightly full. Do not go to the toilet before the transfer. In the morning, take all medications according to your protocol, including vaginal capsules. Do not use perfume that day. Arrive at the clinic with sufficient time in advance.

How long does the transfer take?

The procedure itself is usually quick and takes only a few minutes. After the transfer, you will rest in the procedure room for about 10 minutes and can then go home.

Can my partner be with me in the procedure room?

Yes, the presence of the partner in the procedure room is completely normal.

Are there any restrictions after transfer?

For one week after the transfer, we recommend avoiding sexual intercourse, sitting baths and visits to swimming pools or outdoor pools. Avoid lifting heavy objects and excessive physical exertion.

How long do I have to take medication?

Take medication according to your doctor's instructions until the pregnancy test (hCG) is performed. If the hCG test is positive, you will usually continue taking medication until the 12th week of pregnancy. Always contact your coordinator with the hCG test result, and she will inform you about the next steps.

How may I feel after the transfer?

Feelings after transfer are completely individual. You may experience mild cramps in the lower abdomen, pressure or bloating, but it is also completely normal not to feel any symptoms.

What if I start spotting or bleeding?

The causes can vary – from completely harmless reasons to situations requiring medical assessment. However, never stop taking prescribed medication without consulting your doctor or coordinator.

Donor cells

Who are egg donors and how are they included in the database?

Egg donors are healthy young women aged 18–34, often students or women at the beginning of their professional careers. Each donor undergoes very strict examination in accordance with Czech and European legislation to ensure her safety and the quality of the donated eggs. The examination includes:

  • Clinical and ultrasound examination
  • Hormonal profile
  • Tests for sexually transmitted infections – HIV, HBsAg, HCV, syphilis, chlamydia
  • Blood group and Rh factor
  • Genetic testing – karyotype, presence of mutations in the cystic fibrosis gene, spinal muscular atrophy, Connexin 26 (congenital deafness)
  • Consultation with a geneticist, who approves the donor for donation

Who are sperm donors and how are they included in the database?

Sperm donors are healthy men aged 18 to 35 who voluntarily help couples who cannot conceive a child using their own sperm. They are often students or young men at the beginning of their careers who meet strict health criteria and undergo a thorough approval process and repeated testing.

Each donor must undergo comprehensive examination in accordance with Czech and European legislation, which includes:

  • Laboratory examination
  • Tests for sexually transmitted infections – HIV, HBsAg, HCV, syphilis, chlamydia
  • Blood group and Rh factor
  • Genetic testing – karyotype, presence of mutations in the cystic fibrosis gene, spinal muscular atrophy, Connexin 26 (congenital deafness)
  • Consultation with a geneticist, who approves the donor for donation

How do you match a donor with a couple?

Egg and sperm donors are matched based on a questionnaire completed by the couple before treatment begins. The questionnaire includes information such as hair and eye colour, height or blood type, which allows us to match the donor and recipient as closely as possible. The entire process is handled sensitively and in accordance with Czech legislation, which guarantees complete anonymity of both donors and recipients.

Can I specify what the donor should look like and what characteristics they should have?

Yes. Before starting treatment, the couple completes a preference questionnaire in which they can specify the desired criteria for selecting an egg or sperm donor. Thanks to our extensive database, we are able to select donors who match recipients as closely as possible.

Do you provide a guarantee within the donor programme?

Yes. If the partner's semen analysis result on the day of the donor's ovarian puncture does not show extremely low values (for example less than 1% morphology), the clinic provides a guarantee of obtaining 2 blastocysts.

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